BPT, MSc., PhD.

Department of Basic Medical Sciences, College of Medicine, King Saud bin Abdulaziz University for Health Sciences

King Abdulaziz Medical City – Riyadh, National Guard Health Affairs, Mail Code: 3127
P. O. Box 22490, Riyadh 11426, Kingdom of Saudi Arabia

Academic Appointments:
Assistant Professor of NeuroPhysiology

(966-11-) 429-9999 Ext. 95265


Profile
Dr. Almuklass is an Assistant Professor of NeuroPhysiology in the Department of Basic Medical Science, College of Medicine, King Saud bin Abdulaziz University for Health Science. He obtained a Bachelor degree in Physical Therapy and Medical Rehabilitation Science from King Saud University, and a MSc degree in NeuroPhysiology & Biophysics from Dalhousie University in Halifax, Canada. Dr. Almuklass then obtained his PhD in Integrative NeuroPhysiology of movement from University of Colorado Boulder. During his PhD, he has conducted research starting from basic physiology studies published in Neurophysiology and Experimental Brain Research Journals to clinical trials studies published in Neurorehabilitation and Neural Repair Journal. He also had a research clinic at the NeuroPhysiology Laboratory where he was a consultant seeing patients diagnosed with Multiple Sclerosis and was working with their Rehabilitation specialists to design rehabilitation therapeutic protocols for those patients.

Dr. Almuklass was awarded with a Research Assistant Position at the University of Colorado Boulder for 2.5 years. During that time, he was the PI for multiple projects including two clinical trials; he supervised undergrad and MSc students, teaching them the experimental and analytical techniques regarding their assigned research projects. Also, he was awarded with the Canadian Graduate Excellence Award (10,000$) for his research work. Dr. Almuklass has received national and international awards for excellent conference papers and speeches. He has more than 40 published abstracts and 15 peer reviewed papers. He is currently collaborating with the University of Colorado (Neural Control of Movement Research laboratory). This collaboration is with Professor Roger Enoka, a world pioneer in the Neurophysiology research of aging, fatigue, motor units and multiple sclerosis. Currently, both Dr. Enoka and Dr. Almuklass are developing an NIH grant proposals for innovative and non-invasive therapies for patients diagnosed with Multiple Sclerosis. Dr. Almuklass is currently applying for several grants agencies to support his laboratory.


Education

  • PhD. Integrative Physiology (Neural Control of Movement), University of Colorado Boulder, Boulder, CO, USA. 2017.
  • M.Sc. Physiology & Biophysics, Dalhousie University, Halifax, Nova Scotia, Canada. 2012.
  • Qualifying graduate studies, Dalhousie University, Halifax, Nova Scotia, Canada. 2010.
  • Bachelor of Physical Therapy and Medical Rehabilitation Science, King Saud University, Riyadh, Saudi Arabia.  2007

Clinical Service

Principle investigator for clinical trial:

  • Neuromuscular electrical stimulation improves walking performance in people with multiple sclerosis: double-blind, randomized trial.
  • Augmented TENS can improve motor functions in individuals with multiple sclerosis.

Co-investigator for clinical trial:

  • Neuromuscular electrical stimulation of triceps surae to improve motor function in older adults: double-blind, randomized trial.

Clinical Neurophysiologist for research clinic (2.5 year)

Honors/Awards

  • The first prize of the free paper session at the “Partnership in Rehabilitation: Research into Practice Symposium” Rehabilitation Hospital, King Fahad Medical City, 2017
  • Best Graduate Poster Presentation at the American Society of Biomechanics meeting,  2016
  • PhD degree Scholarship in Integrative Physiology at University of Colorado Boulder, from KSAU-HS,  2013- 2017
  • Graduate Excellence Award, 10,000$, Canada, 2012
  • M.Sc degree Scholarship in Physiology at Dalhousie University from KSAU-HS.  2010-2012 


Memberships

  • Co-chair and Coordinator for the Faculty and Student Research Board, College of Medicine, 2018
  • Member of the University Research Board at King Saud bin Abdulaziz University for Health Science, 2017
  • Voting Member of the Institutional Review Board (IRB) at University of Colorado Boulder, 2014- 2016 
  • Member of American College of Sport Medicine, 2014
  • Member of American Society of Physiology, 2015
  • Associate member of The Association for Research in Otolaryngology, 2011-2012 
  • Member of the Saudi Physiotherapy Association, 2005- 2008
  • Member in the Saudi Sports Medicine Association, 2005- 2008

Research Focus

  • Neurophysiology and Neural Control of Movement
  • Therapeutic electrical stimulation (tDCS, TMS, sensory stimulation)
  • Electromyography (Surface EMG, subcutaneous motor units recording, high density EMG) 
  • Manual dexterity and walking determinants in healthy aging and patients with Neurological disorder
  • Translational neurophysiology research for healthy aging, multiple sclerosis and spinal cord injuries

Active Research Grants , Collaboration, and Journal International Reviewer:

  • Grants proposal are pending for approval
  • IEEE Transactions on Biomedical Engineering
  • Medicine & Science in Sports & Exercise

Collaboration

  • Prof. Roger Enoka, the Neurophysiology of Movement Laboratory, University of Colorado Boulder, USA.
  • Dr. Suliman Alghnam, Population Health, KAIMRC, Saudi Arabia

Scientific Journal Reviewer

  • Medicine & Science in Sports & Exercise
  • IEEE Transactions on Biomedical Engineering
  • The Open Neurology Journal
  • Ergonomics Journal 

Publications

  1. Hamilton LD, Mani D, Almuklass AM, Davis L, Vieira T, Botter A, Enoka RM. Electrical nerve stimulation modulates motor unit activity in contralateral biceps brachii during steady isometric contractions. Journal of Neurophysiology, in press 2018. DOI: 10.1152/jn.00235.2018.   https://www.ncbi.nlm.nih.gov/pubmed/30156959 .
  2. Almuklass AM, Feeney DF, Mani D, Hamilton LD, Enoka RM. Peg-manipulation capabilities of middle-aged adults have a greater influence on pegboard times than those for young and old adults. Exp Brain Res 236:2165-2172, 2018. DOI: 10.1007/s00221-018-5294-3. https://www.ncbi.nlm.nih.gov/pubmed/29785485
  3. Mani D, Almuklass AM, Hamilton LD, Vieira T, Botter A, Enoka RM. Motor unit activity, force steadiness, and perceived fatigability are correlated with mobility in older adults. Journal of Neurophysiology, in press 2018. DOI: doi: 10.1152/jn.00192.2018. https://www.ncbi.nlm.nih.gov/pubmed/30044670
  4. Almuklass AM, Davis L, Hamilton LD, Vieira T, Botter A, Enoka RM. Motor unit discharge characteristics and walking performance of individuals with multiple sclerosis. Journal of Neurophysiology 119:1273-1282, 2018. DOI: 10.1152/jn.00598.2017. https://www.ncbi.nlm.nih.gov/pubmed/29357453   
  5. Mani D, Almuklass AM, Amiridis IG, Enoka RM. Neuromuscular electrical stimulation can improve mobility in older adults with two different pulse-width and frequency combinations: double-blind, randomized trial. Experimental Gerontology 108: 269-275, 2018. DOI: 10.1016/j.exger.2018.04.018. https://www.ncbi.nlm.nih.gov/pubmed/29738790 .    
  6. Almuklass AM, Davis L, Hamilton LD, Hebert JR, Alvarez E, Enoka RM. Pulse width does not influence the gains achieved with neuromuscular electrical stimulation in people with multiple sclerosis: double-blind, randomized trial. Neurorehabilitation & Neural Repair 32:84-93, 2018. DOI: 10.1177/1545968317753681. https://www.ncbi.nlm.nih.gov/pubmed/29366377 
  7. Almuklass AM, Feeney DF, Mani D, Hamilton LD, Enoka RM. Peg-manipulation capabilities during a test of manual dexterity differ for persons with multiple sclerosis and healthy individuals. Exp Brain Res 23:3487-3493, 2017. DOI: 10.1007/s00221-017-5075-4. https://www.ncbi.nlm.nih.gov/pubmed/28849332 .
  8. Capobianco RA, Almuklass AM, Enoka RM. Manipulation of sensory input can improve stretching outcomes. Eur J Spo Sci. 2018. DOI.org/10.1080/17461391.2017.1394370. https://www.ncbi.nlm.nih.gov/pubmed/29105593 .
  9. Dideriksen JL, Feeney DF, Almuklass AM, Enoka RM. Control of force during rapid visuomotor force-matching tasks can be described by discrete time PID control algorithms. Exp Brain Res (2017). DOI:10.1007/s00221-017-4995-3. https://www.ncbi.nlm.nih.gov/pubmed/28555275.
  10. O’Leary TP, Shin S, Fertan E., Dingle RN., Almuklass A, Gunn RK., Yu Z, Wang J, Brown R E. Reduced acoustic startle response and peripheral hearing loss in the 5xFAD mouse model of Alzheimer’s disease. Genes Brain Behav 16: 554-563, 2017. DOI: 10.1111/gbb.12370. https://www.ncbi.nlm.nih.gov/pubmed/28133939 .
  11. Hamilton LD, Thomas E, Almuklass AM, Enoka RM. A framework for identifying the adaptations responsible for differences in pegboard times between middle-aged and older adults. Experimental Gerontology 97:9-16, 2017. DOI: 10.1016/j.exger.2017.07.003. https://www.ncbi.nlm.nih.gov/pubmed/28688836
  12. Almuklass AM, Price RC, Gould JR, Enoka RM. Force steadiness as a predictor of time to complete a pegboard test of dexterity in young men and women. Journal of Applied Physiology. 2016; 120(12):1410–7. DOI: 10.1152/japplphysiol.01051.2015. https://www.ncbi.nlm.nih.gov/pubmed/27103655
  13. Liu L, Wang H, Shi L, Almuklass A*, He T, Aiken S, et al. Silent Damage of Noise on Cochlear Afferent Innervation in Guinea Pigs and the Impact on Temporal Processing. PLoS ONE. 2012;7(11). DOI: 10.1371/journal.pone.0049550. (* first co-author) https://www.ncbi.nlm.nih.gov/pubmed/23185359 
  14. Amiridis IG, Mani D, Almuklass A, Matkowski B, Gould JR, Enoka RM. Modulation of motor unit activity in biceps brachii by neuromuscular electrical stimulation applied to the contralateral arm. Journal of Applied Physiology. 2015;118(12):1544–52. DOI: 10.1152/japplphysiol.00031.2015. https://www.ncbi.nlm.nih.gov/pubmed/25930023
  15. Shou-huan H, Almuklass A, Wang J, Xiao-jie. The effect of sound intensity on temporal resolution of neurons in inferior colliculus. Chinese Journal of Otology. 2013;11(4): 591-595. https://academic.naver.com/article.naver?doc_id=110677543.

 

    Conferences Papers, Oral Presentations, and Posters:

  1. Almuklass AM, Davis L, Hamilton L, Hebert JR, Alvarez E, Enoka RM. Neuromuscular electrical stimulation improves walking performance in people with multiple sclerosis: double-blind, randomized trial. Med Sci Sports Exerc 49 (5S): 49(5S):632, 2017. doi: 10.1249/01.mss.0000518662.21554.c6.
  2. Almuklass AM, Davis L, Vieira T, Botter A, Derqaoui K, Hamilton L, Hebert JR, Vollmer TL, Alvarez E, Enoka RM. Neuromuscular determinants for walking performance in individuals with multiple sclerosis. Med Sci Sports Exerc 48 (5S): 712, 2016.
  3. Almuklass AM, Price RC, Enoka RM. Steadiness Test Performance is Associated with Manual Dexterity among Young Adults. Med Sci Sports Exerc. 2015;47:660.
  4. Almuklass A, Feeney D, Mani D, Hamilton LD, Price RC, Enoka RM. Association between timing and force characteristics during the grooved pegboard test for healthy adults and individuals with multiple sclerosis. American Society of Biomechanics 40 (Suppl 1): 000-000, 2016.
  5. Almuklass A, Price R, Enoka RM. An expanded set of steadiness tests significantly improves the ability to predict pegboard times of young adults. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, April 17-18, 2015.
  6. Almuklass AM, Feeney D, Capobianco R, Enoka RM. Augmented tens can improve motor functions in individuals with multiple sclerosis. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, 2017.
  7. Almuklass A, Price R, Enoka RM. Pegboard performance of young adults depends on decision-making strategies rather than functional constraints. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, April 17-18, 2015.
  8. Almuklass A, Aiken S, Wang J. The functional and morphological changes by noise without causing hearing loss: a comparison between mice and guinea pigs. The 2012 MidWinter Meeting of Association for Research in Otolaryngology, San Diego, California, USA, Feb 25-29, 2012.
  9. Almuklass AM, Feeney D, Capobianco R, Enoka RM, Sensory Stimulation Can Improve Motor Functions in Individuals with Multiple Sclerosis. American Society of Biomechanics 41 (1): 2017.
  10. Almuklass A, Davis L, Knowles S, Closson-niese T, Bersee L, Vieira T, Botter A, Derqaoui K, Hamilton L, Hebert JR, Enoka RM. Dorsiflexor muscle activity predicts walking performance in individuals with multiple sclerosis. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, April 15-16, 2016.
  11. Almuklass A, Feeney D, Mani D, Hamilton LD, Price RC, Enoka RM. Grooved pegboard test timing and force characteristics for healthy adults and individuals with multiple sclerosis. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, April 15-16, 2016.
  12. Almuklass AM. Modulation of motor activity with electrical nerve stimulation of sensory nerve fibers. The International Motoneuron Society, June 11-14, 2018, Boulder, Colorado, USA.
  13. Almuklass AM, Mani D, Vieira T, Botter A, Enoka RM. Associations between motor unit activity during steady isometric contractions with lower leg muscles and mobility in older adults and persons with multiple sclerosis. XXII Congress of the International Society of Electrophysiology and Kinesiology, Dublin, Ireland, June 30 – July 2, 2018.
  14. Capobianco R, Almuklass AM, Enoka RM. Stretching combined with tens or self-massage has differential effects on ankle flexibility. Medicine & Science in Sports & Exercise. 49(5S):839. doi: 10.1249/01.mss.0000519255.88800.e5.
  15. Price RC, Almuklass AM, Enoka RM. Determinants of dexterity in young adults. Med Sci Sports Exerc 47 (Suppl 1): 657-666, 2015.
  16. Capobianco R, Almuklass AM, Enoka RM. Stretching combined with tens or self-massage has differential effects on ankle flexibility. Med Sci Sports Exerc 49 (5S):839, 2017. doi: 10.1249/01.mss.0000519255.88800.e5.
  17. Mani D, Almuklass AM, Vieira T, Botter A, Enoka RM. Differences in Mobility Among Older Adults are Associated with Motor Unit Activity and Muscle Strength. Med Sci Sports Exerc 49(5S):1030, 2017. doi: 10.1249/01.mss.0000519828.94459.a5
  18. Davis L, Almuklass AM, Hamilton LD, Vieira T, Botter A, Enoka RM. Motor Units Discriminated From High-density, Surface Electromyography Require Careful Scrutiny. Med Sci Sports Exerc 49(5S):776, 2017. doi: 10.1249/01.mss.0000519069.79872.07.
  19. Davis LA, Almuklass A, Derquaoi K, Hamilton L, Hebert J, Vollmer TL, et al. Neuromuscular electrical stimulation can improve walking endurance in individuals with multiple sclerosis. Med Sci Sports Exerc. 2016;48:713. doi: 1249/01.mss.0000487142.45225.54.
  20. Mani D, Almuklass AM, Amiridis IG, Enoka RM. Neuromuscular electrical stimulation can improve walking endurance in old adults. Med Sci Sports Exerc. 48:760, 2016. doi: 10.1249/01.mss.0000487282.57928.
  21. Mani D, Almuklass A, Amiridis I, Gould J, Matkowski B, Enoka R. Effect Of Neuromuscular Electrical Stimulation On Contralateral Motor Unit Activity In Biceps Brachii. Med Sci Sports Exerc. 2015; 47:657.
  22. Mani D, Almuklass AM, Hamilton LD, Vieira T, Botter A, Enoka RM. High-density surface EMG recordings of calf muscle activity in older adults during walking. Annual Meeting of the American Society of Biomechanics, Boulder, Colorado, USA, August 2017.
  23. Hamilton LD, Thomas E, Derqaoui K, Almuklass A, Enoka RM. Determinants Of Manual Dexterity In Middle-aged And Older Adults. Med Sci Sports Exerc. 2016;48:824.
  24. Feeney D, Dideriksen J, Almuklass A, Enoka RM, Grooved pegboard performance in young adults can be predicted by PID-controller based models of isometric force. American Society of Biomechanics 40 (1):2016.
  25. Mani D, Almuklass AM, Amiridis IG, Enoka RM. Variance in motor function of older adults is associated with motor unit activity in calf muscles. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, 2017. 
  26. Hamilton LD, Thomas E, Derqaoui K, Almuklass A, Enoka RM.Identification of latent variables underlying manual dexterity in middle-aged and older adults. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, 2017. 
  27. Davis L, Almuklass AM, Hamilton LD, Vieira T, Botter A, Enoka RM. Analysis of the quality of motor unit signals discriminated from high-density, surface electromyography in the calf muscles of persons with multiple sclerosis. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, 2017. 
  28. Amiridis IG, Mani D, Almuklass A, Gould JR, Matkowski B, Enoka RM. Modulation of motor unit activity in biceps brachii in response to neuromuscular electrical stimulation applied to the contralateral arm. European Congress of Sport Sciences, Amsterdam, Netherlands, July 2-5, 2014.
  29. Davis L, Almuklass A, Closson-niese T, Knowles S, Bersee L, Hamilton L, Hebert JR , Enoka RM. The influence of neuromuscular electrical stimulation on walking in persons with multiple sclerosis. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, April 15-16, 2016.
  30. Enoka RM, Almuklass AM, Davis L, Zijdewind I. Fatigue can be unrelated to fatigability in clinical cohorts. European Congress of Sport Sciences, Vienna, Austria, July 6-9, 2016.
  31. Gould JR, Mani D, Almuklass A, Amiridis IG, Matkowski B, Enoka RM. Motor unit activity in biceps brachii due to neuromuscular electrical stimulation of the contralateral elbow flexors. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, April 17-18, 2015.
  32. Hamilton LD, Thomas E, Derqaoui K, Almuklass A, Enoka RM. Age-related differences in force steadiness during single- and double-action tasks. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, April 15-16 2016.
  33. Liu L,Shi L,Fu A, Almuklass A, Aiken S,Wang J. Evaluation of cochlear temporal acuity by using time-stressed stimuli. The 2012 MidWinter Meeting of Association for Research in Otolaryngology, San Diego, Calfornia, USA, Feb 25-29, 2012.
  34. Mani D, Almuklass A, Amiridis IG, Enoka RM. Neuromuscular electrical stimulation of triceps surae to improve motor function in older adults. Rocky Mountain Chapter of the American Society of Biomechanics, Estes Park, CO, April 15-16, 2016.
  35. Al Harbi F, Alammar J, Alnumani M, Albaqmi K, Alharbi T, Mahzari M, Almuklass AM. Predictors of manual dexterity/hand function in health and disease: short review. Health Professional Conference, April1 17-19, 2018, KSAU-HS, Riyadh, KSA.
  36. Davis L, Almuklass AM, Alenazy M, Feeney DF, Vieira A, Botter A, Enoka RM. Force steadiness for the dorsiflexors of the less-affected leg does not differ between individuals diagnosed with multiple sclerosis and healthy control subjects. The International Motoneuron Society, June 11-14, 2018, Boulder, Colorado, USA.
  37. Hamilton LD, Mani D, Almuklass AM, Davis L, Vieira T, Botter A, Enoka RM. Electrical nerve stimulation frequency and pulse duration influence motor unit discharge characteristics of the elbow flexors. The International Motoneuron Society, June 11-14, 2018, Boulder, Colorado, USA.
  38. Alfawzan AI, Alshahrani SA, Alswaidan AT, Alkharaan AI, Aldossary HS, Almuklass AM. Is History of Type 1 Allergic Diseases Increase the Risk of Developing Multiple Sclerosis? Health Professional Conference, Jan 15-17, 2019, KSAU-HS, Riyadh, KSA.

 Published Theses:

  1. Almuklass AM. The Functional and Morphological Changes by Noise without Causing Hearing Loss: A Comparison between Mice and Guinea Pigs, Faculty of Graduate Studies Online Theses, Dalhousie University. May 2012.
  2. Almuklass AM. Neuromuscular determinants of manual dexterity and walking performance in healthy individuals and persons with multiple sclerosis. Faculty of Graduate Studies Online Theses, University of Colorado Boulder. July 2017.